Moderate sand yielding technology can exploit crude oil with low cost and high efficiency, and improve the well productivity effectively. This technology needs to control sand concentration of the produced fluid in a certain range, which requires real-time monitoring wells sand conditions. In order to study the method of real-time monitoring of the sand signal, the laboratory has developed a system of high frequency vibration signal used for monitoring the signal of sand. Through the time-frequency analysis of vibration signals of different sizes of sand hitting on the pipe wall in the laboratory simulation of sand production, the frequency range of the characteristic frequency of vibration signals reflecting the information of sand is screened out between 10-12 kHz, which proves the feasibility of the pipeline high-frequency vibration signal monitoring system. It has an important guiding significance for further study on sanding monitoring.