Artificial edge water flooding technology can enhance oil recovery of the complex fault-block reservoir effectively. Influencing factors on the effect of the artificial edge water flooding are various. The sensibility of the influencing factors on the oil displacement effect is not clear，which has limited reservoir optimization and execution of planning. Taking the complex fault-block reservoir with obvious field result as an example，the effect of reservoir influencing factors on the degree of enhancing oil recovery by the artificial edge water flooding were studied using reservoir numerical simulation so as to provide basis for block optimization. Eight influencing factors were determined covering three aspects of structure，reservoirs and fluid. The influence mechanism was interpreted based on the theory of reservoir physics and reservoir percolation.Optimization standards of the complex fault-block reservoir were established for the artificial edge water flooding. Quantified standards and relationship charts of single reservoir factors versus enhanced oil recovery were given.