In order to solve the problem of“difficult to inject，difficult to produce”under the condition of thermal recovery in low permeability carbonate heavy oil reservoir of Syria O oilfield，experiments of self-imbibition and oil displacement were conducted for the cores in O oilfield. Imbibitions rule and displacement effect of formation water and thin film spreading agent（TFSA）solution were researched under 50 and 150 ℃. The self-imbibition experiment result shows that the wettability of the carbonate cores in O oilfield turns from obvious oil-wet or weak oil-wet under original conditions to waterwet or weak water-wet after TFSA imbibition，and thus wettability inversion is realized. The displacement experiment result shows that compared with steam injection at 150 ℃，the thermal compound chemical technology，steam injection with TFSA，can significantly reduce steam injection pressure by about 2 MPa and the displacement efficiency is increased by about 10%. After wettability inversion of the rocks，water is easy to enter the pore of the rocks under capillary force which is a driving force during water displacing oil and the difficulty of“difficult to inject”may be solved. High temperature can reduce crude oil viscosity and the percolation ability of crude oil is improved，and the difficulty of“difficult to produce”may be solved. Therefore，the thermal compound chemical technology is a feasible method for enhancing oil recovery in O oilfield and similar low permeability carbonate heavy oil reservoirs.