In order to clarify the control of Paleogene faulting on subsag morphology，features and migration of sedimentation-subsidence center in different sedimentary period in Dongpu Sag，the structure of Dongpu Sag was interpreted and analyzed using the seismic data，drilling，logging data and heavy magnetic data. The results show that it is a universal basin in the sediment of the fourth member of Shahejie Formation in Dongpu Sag. Then the intense fault movement resulted in the division of sag during the sedimentation of the lower third member of Shahejie Formation. A framework characterized of multifaults，multiuplifts and multisubsags formed during the sedimentation of 1-4 sand group in the middle third member of Shahejie Formation. The activity of the second-level and the third-level faults formed in the early stage were gradually weakened or stopped after the sedimentation of the second member of Shahejie Formaiton. Large numbers of third-level and the fourth-level faults formed，and the framework characterized of multifaults-multiuplifts-multisubsags became more obvious. The equilibrium crustal gravity subsidence resulted in the seesaw-type differentiation of the strata and controlled the evolution of subsags combined with the fault activity. The Paleogene fault activity controlled the subsag evolution and the distribution of hydrocarbon source rocks in Dongpu Sag，and the occurrence of the fault controlled the morphology of subsag and the type of kerogen.