A large number of buried hill oil reservoirs are developed in the inner uplifts of Jiyang Depression. However，hydrocarbon accumulates in shallow layers instead of the low uplift in Changdi area. At present，research on the genetic mechanism of hydrocarbon accumulation is insufficient in this area. The structure is an important factor controlling the hydrocarbon accumulation. For this reason，based on the detail seismic data interpretation and hydrocarbon geochemical data analysis，the characteristics of the strike-slip faults and their control on the hydrocarbon are analyzed. The results show that Changdi fault is formed in the Cenozoic，with obvious dextral strike-slip. The middle part of Changdi fault is pressurization flexure in“S”shape of the strike-slip fault caused by pressure increasing，the fault plane is tightly closed，and the strata are compressed and uplifted to form small anticlines and fault-nosed traps. The southern and northern part of Changdi fault is depressurization flexure in“S”shape of the strike-slip fault caused by pressure releasing，the fault plane is opened and destroys the early traps，which is not conducive to hydrocarbon accumulation. The hydrocarbon accumulation mode in strike-slip compressed sections in Changdi low uplift is mainly characterized by shallow hydrocarbon accumulation，multihydrocarbon sources supply and multi-transportation pathways.