Rich in hydrocarbon resource，Oman Basin develops multiple sets of hydrocarbon accumulation. The previous studies mainly focused on the source-reservoir assemblages in the Paleozoic and Mesozoic reservoirs，but less on those in Cenozoic reservoirs. In this paper，the Paleogene Umm Er Radhuma carbonate reservoir in the north of Oman Basin had been studied to analyze the reservoir characteristics，hydrocarbon resource，migration path，and accumulation features and establish hydrocarbon accumulation patterns to discuss the main controlling factors based on data about crude oil composition，core，logging，and seismic combined with documents on regional tectonic evolution，source rock distribution and burial history. The results show the favorable reservoir-cap conditions. On one hand，the Paleogene Umm Er Radhuma carbonate formation in the north of Oman Basin is buried shallowly and compacted weakly with developed pores. On the other hand，the Rus gypsum horizon in the upper part can be used as the high-quality caprock. Also，according to the results，the hydrocarbon source is the organic-rich marl in the Cretaceous Natih carbonate formation and the hydrocarbon generation center is located in the Fahud salt basin in the eastern work area. In accordance with the geochemical analysis of core，the hydrocarbon source in the work area is not mature；the crude oil in the Umm Er Radhuma carbonate reservoir is from the Fahud salt basin in which the generated hydrocarbon is migrating upwards and westwards along the fault and plane of unconformity. The plane of unconformity on top of the Cretaceous system，the collapse channel of dissolution fault，and local microstructure are the key factors for hydrocarbon accumulation in the Paleogene Umm Er Radhuma carbonate reservoir in the north of Oman Basin and are characterized by“fault communication，migration along the plane of unconformity，and local microstructure in control”.