During CO2 flooding in low permeability reservoirs，solid-phase deposition may damage the reservoirs. The current measurement methods cannot quantitatively characterize the solid-phase deposition in a direct and accurate manner.With this regard，a new microscopic visualized experimental method for solid-phase deposition was proposed for comparative analysis of solid-phase deposition between different development modes，and the experiment was performed on solidphase deposition with different CO2 injection rates and injection pressure levels. The results show that the solid-phase deposition is mainly composed of colloid and asphaltene. Specific threshold pressure is observed in the solid-phase deposition of CO2 flooding，and the deposition area is mainly located in the miscible area. The deposition law shows a trend of slowly increasing，rapidly rising，and gradually slowing down，and the precipitation and dissolution process of solid-phase deposition is reversible to a certain extent. According to the experimental results，the injection pressure level for CO2 flooding should be lower than the threshold pressure of solid-phase deposition to inhibit it significantly and reduce the damage of solid-phase deposition to the reservoirs during CO2 flooding. The field applications of experimental results effectively reduce the damage to the reservoirs and increase the potential for sustainable development of the oilfield.