Viscosity-reducer foam flooding combines the advantages of emulsification of viscosity-reducers and selective blocking of foam to further enhance oil recovery in deep low-permeability heavy oil reservoirs during the later development stages. The suitable concentration of viscosity-reducing foam agents were selected according to the viscosity-reducing effect,foaming performance and foam stability of the agents by laboratory experiments. Meanwhile,the characteristics and recovery effects of viscosity-reducer foam flooding under different displacement modes were compared by single-core displacement experiments, and the diverting capacity of viscosity-reducing foam at various permeability ratios were investigated by parallel core experiments,and thus the enhanced oil recovery (EOR)mechanisms of viscosity-reducer foam flooding ware defined. The results demonstrate that the viscosityreducing agents facilitate the emulsification and viscosity reduction of heavy oil, while the foams block large pore throat and inhibit N2 channeling during viscosity-reducer foam flooding. Combination of the both can improve the sweep coefficient and displacement efficiency,increase displacement pressure differential,and lower the water cut. Furthermore,the viscosity-reducer foam flooding can enhance the oil recovery by an additional 13% based on the viscosity-reducer flooding. In heterogeneous conditions,viscosityreducer foam flooding decreases the high-permeability core channeling to direct the flow towards low-permeability cores,thereby exerting an emulsification and viscosity-reducing effect. Finally,this expands the swept volume and simultaneously enhances the displacement efficiency. While the viscosity-reduce foam flooding significantly enhance the oil recovery of deep low-permeability heavy oil reservoirs by optimizing the oil flow distribution,enhancing emulsification,and reducing heavy oil viscosity, thus providing an effective strategy for efficient development of deep heavy oil reservoirs.