In the CO₂ flooding process，the optimization of the uniformity degree of the front is crucial for improving the effectiveness of CO₂ flooding. To address the issue of uneven CO₂ flooding front in the reservoirs caused by planar heterogeneity of the reservoir and the influence of injection-production well patterns，a well group model was established to simulate the non-uniform front during the injection-production process. Through an automatic optimization algorithm，a CO₂ flooding injection-production parameter optimization method was developed to achieve control over front uniformity. Using reservoir engineering methods，the reasonable range of injection-production parameters during the optimization process was defined.Parameter optimization applications were studied for three injection schemes in the F142 well group in Shengli Oilfield：continuous gas injection，injection-production coupling，and water-alternating-gas（WAG）injection. The effects of front optimization were evaluated using metrics such as the storage ratio，produced gas-oil ratio（GOR），and oil exchange ratio. The results show that optimizing the uniformity degree of the CO₂ front simultaneously increases the CO₂ storage ratio，reduces the overall produced GOR，and enhances the oil exchange ratio in CO₂ flooding injection-production parameter optimization. For the F142 well group，earlier simultaneous gas breakthrough in production wells is more favorable for oil displacement，while later gas breakthrough is more favorable for CO₂ storage.