The heavy oil wells are faced with problems such as high temperature and corrosion in the process of development of ISC in Xinjiang oilfield.This article optimally designed a set of cement system of resistant CO2 corrosion in the high temperature conditions.The indoor evaluation test results showed that the compressive strength of cement stone is 13.8 MPa after the high temperature and CO2 corrosion maintenance，the strength corresponded to the security of analysis of the stress state.The permeability and porosity of cement stone suffered little change，the morphology of cement stone was density and the structure was homogeneous after the stone cement corrosion.It also had good strength and toughness and properties，so it could meet the requirements of high temperature cementing project.This cement system used in 9 wells in Xinjiang oilfield，the results showed that the cementing quality achieved 100%，it ensured the cement quality and production safety and provide vast space to improve heavy oil recovery for Xinjiang old oilfield.