In order to solve the problems of high cost and long cycle in the interwell connectivity research of reservoirs in Liuzhongdong block，Junggar basin，the connectivity coefficient of the oil and water wells was inversed using multiple linear regression mathematical method on the basis of dynamic data including fluid production of oil wells and water injection of water wells. The research results have been verified by tracer data. It shows that there are 4 connectivity types between oil and water wells：single well onrush，single connectivity，one-way connectivity and multidirectional connectivity. The factors controlling the connectivity are mainly affected by the configuration element，fault，physical properties of reservoirs，reservoir stimulation etc. Single well onrush and single connectivity types develop in layer S74 and layer S73 of fan root system，which are mainly controlled by the physical properties of the reservoirs. Single connectivity and one-way connectivity types mainly develop in layer S72 and layer S71 of middle fan system，which are controlled by the configuration unit.