There is usually strong bottom water energy after water flooding in Tahe fractured-vuggy carbonate reservoir.Thus the bottom water will have influence on remaining oil in subsequent water flooding and gas drive continuously，which has vital significance. Visible physical models were applied to simulation experiment of water flooding and gas drive. Interaction of strong bottom water and subsequent injected water and gas was displayed intuitively. Related influencing factors were discussed. Experimental results show that the strong bottom water has a promoting role on the subsequent development of remaining oil. Principle of interaction among bottom water and water injection，gas injection was different in various ways.In addition，the bottom water strength，fracture cave combination，gravity and other factors will influence this interaction. Research results provide experimental basis for EOR plan design of subsequent water flooding and gas drive. Quantitative matching of injected water and gas with the strong bottom water should be the key of subsequent further research.