Coalbed Methane (CBM) gas has a complex process of desorption-diffusion-seepage in the stage of development, causing the changes of pore structure and impaction on production to some extent. Therefore, it is necessary to take the self-regulating effect on pore changes into consideration when studying the material balance of CBM reservoirs. On the basis of the establishment of the model, we infer the CBM reservoir material balance equation. Combined with gas, aquatic energy equation and the relative permeability curves as well as the deviation factor with increasing pressure, we conduct dynamic predict of CBM reservoir production. It is of high reliability by matching the predicted results and the actual production data. Based on the parameter sensitivity analysis,we obtain that in the late production of CBM wells, on the condition of different sensitivity, reservoir pressure and time exhibit an exponential correlation, and the impaction of reservoir pressure on gas well production. Comprehensive analysis of the results shows that the CBM reservoir production of good self-regulating effect, high permeability, high Langerhans pressure and big seam thickness is relatively high.