The eastern exploration area of Shengli oilfield has fully entered the subtle reservoir exploration stage. We should think strategically and discuss on several dialectical relationship of exploration work. Firstly, we deal with the relationship between the subjective and the objective correctly. That is, we handle correctly the relationship between geological researchers as the subject and the geological body being studied and described as the object. Secondly, we handle relationship between the known and the unknown. We should not stress“absolute”concept, and draw artificially absolute limits, exploration work should follow“cycle, spiral”awareness rules. Thirdly, we handle relationship between technical progress and practical application, and determine that the researchers are the decisive factor, it is the basic principle that we combine with advanced technology and practical application. To think these relationships dialectically, it is conducive to ensure the exploration key of“improving quality and efficiency”. We make positive contribution for oilfield to achieve sustainable development and the successful completion of the task granted by history.