Water crossflow is one of the main problems encountered during the development of homogeneous reservoirs. Multi-cycle operations of water shutoff are short of detailed description. In this paper, the visible plate models are designed, and systematical research on parameter optimization is launched with ideal modal, while the best position to deploy plugging agents is also studied in modals with bended channels. The results show that there is a limit on the injection volume, and when it equals to 0.1 PV, the operation may get economical success. The sweep efficiency can be higher with the deeper location, and different styles of remaining oil distribution show different results. When the remaining oil is near the producing well, the plugging agents should be put deeper; while the range is little with the remaining oil adjacent to injecting well. For models with worm-shaped channels, the best location for plugging agents is just after breakpoint near injecting well, which can make full use of the pressure drop (flowing rate) and fluid diverting. Under this condition,the synergism, as well as the recovery rate, can both reach the optimum.