In order to further enhance oil recovery in Zhenjing low permeability reservoirs, the air foam flooding EOR technology was researched through core displacement experiments. The experimental results suggested that air foam flooding after water flooding could improve oil displacement efficiency in low permeability reservoirs. Meanwhile, the development effect of following water flooding could be enhanced. The displacement efficiency for initial water flooding was 29.06%, and the following air foam flooding improved it for more than 10 percentage points. After water flooding again, the oil displacement efficiency could reach 45.42% for the average. The results also indicated that increasing injection rate or injection volume of air foam could improve the ultimate oil displacement efficiency with a shortened time of gas breakthrough, and gas channeling had little effect on oil recovery. Air foam flooding EOR technology using alternative injection of foaming agent solution and air was technically feasible for low permeability reservoirs based on water flooding.