The relationship between formation water type and fillings material was established based on the chemical interaction between the fluid and the rock，which is helpful for accurate prediction of favorable reservoir development. Starting with the analysis of the relationship between the formation water property and the diagenetic mineral，the sedimentary microfacies and diagenetic facies developed in the lower Es3 in Jiangjiadian-Wawu area were analyzed comprehensively using microscopic analysis techniques. The results show that water distributary channel，underwater distributary channel，mouth bar and front sheet sand develop mainly in the target formation of the study area. Three types of formation water assemblages, CaCl2 type, CaCl2-NaHCO3 type and NaHCO3-Na2SO4 type, were identified, and they mainly develop in areas of the formation water block zone, the transition zone and the stagnation zone, repecitvely. The specific fluid-rock chemical interaction in the study area was determined by rock mineral difference and formation water properties，which has obvious characteristics of A stage in the middle diagenesis process and is controlled by sedimentary microfacies and diagenetic facies.Five types of diagenetic facies were identified and named as weak-compacted clay-filled and ferrodolomite-cemented facies，moderate-compacted clay-filled and carbonate-cemented facies，trong-compacted carbonate-cemented facies，strong-compacted clay-filled facies，strong-compacted quartz and feldspar-corroded facies. Different diagenetic facies have different diagenetic effects，which determines the way and the characteristics of reservoir dilatation and densification.The characteristics of reservoir development controlled by different sedimentary microfacies and diagenetic facies were evaluated by classification through superposition of diagenetic facies，sedimentary microfacies and isopach charts of sand bodies.