Pore-fracture media with different scales are formed after volume fracturing of horizontal wells in tight reservoirs. The flow law of fluid in different scale media is different. It is difficult to predict the production. Based on summary of the previous understanding of the flow law of fluid in different scale media，the production prediction model of the volume fractured horizontal well in the tight reservoir was established，and its accuracy was proved by actual oilfield data. The influencing factors on production of the volume fractured horizontal well in the tight reservoir were analyzed. The stress sensitivity coefficients of different media was sorted based on their influence on production. From great to small，they are stress sensitivity coefficient of the secondary fracture，stress sensitivity coefficient of the main artificial fracture and stress sensitivity coefficient of the matrix. The high-speed nonlinear coefficient has great influence on the production，while the start-up pressure gradient has little influence on the production.