Problems on strata & well pattern appeared at extra high water cut stage in Daqing Oilfield，and contradiction should be relieved and development effect should be improved through adjustment. Physical modeling and numerical simulation were applied to understand the mechanisms of interbedded and plane contradiction at the extra high water cut satge.Based on the theoretical research，the technical and economic limits，principles，and pattern of strata & well pattern reconstruction were determined，the field trials was carried out in X pilot area，and the recovery efficiency increased from 51.30% to 56.79%. Research and practice on the strata & well pattern reconstruction in Daqing Oilfield indicate that the difference of permeability is the internal cause of interlayer and well interference，the uniformity of well space is the external cause of the well interference，which is the easiest to be artificially improved. The difference of water saturation affects flow among layers and wells under the action of the internal and external causes. Development effect can be improved by dividing strata and development object in more detail and by thickening well pattern appropriately.