The conventional technology regards the process of deep water shutoff and profile control as a dynamic nonlinear problem with a long delay. The conventional evaluation methods for near-well water shutoff and profile control will cause large deviations. Therefore，considering the effect on water injection wells and oil wells，a comprehensive evaluation index for deep water shutoff and profile control is constructed. On this basis，the Hurst index of time series of the comprehensive evaluation index is calculated through V/S analysis and the stability of the time series is analyzed. A comprehensive evaluation method of deep water shutoff and profile control is developed. This method is applied to a certain well group subject to deep water shutoff and profile control in Gudao Oilfield. The results demonstrated that the measures of deep water shutoff and profile control began to take effect after 30 days. The Hurst index was greater than 0.5，and VN，characterizing the stability of the time series，continued to increase. It is predicted that the effect of those measures on this well group will last for a certain period of time，and this coincides with the change in the dynamic curves of production. It is proven this method can provide reliable guidance for the field application of deep water shutoff and profile control.