To improve the low productivity and acidification feasibility of volcanic rock reservoirs in Huizhou Sag，Pearl River Mouth Basin，we analyze the characteristics of the target reservoir. The lithology is mainly andesite with a tight core，low porosity，low permeability，and high temperature. Through the research on the high-temperature-resistant and strongly corrosive acid solution systems，we select an acid solution system with a 40.29%-61.29% corrosion rate of rock debris，and the main agent is composed of 12% hydrochloric acid and 30% organic fluorosilicic acid. A corrosion inhibitor that is resistant to as high as 180 ℃ and consists of 4% HZ-1 and 0.7% HZ-2 is selected. Its corrosion rate is 59.33-63.86 g（/ m2·h），which can satisfy the industrial standard. The combined process of deflagration fracturing and acidification can enhance the ability of acidification stimulation. When the skin factor is 0-3，the stimulation ratio is 1.4-4.3，much higher than the prediction data of matrix acidification. The obvious advantages of the combined process of deflagration fracturing and acidification are confirmed by the application of typical well conditions in low permeability reservoirs in China’s offshore oilfields.The acidification of volcanic rocks in this area can be used as a reserve technology to further increase the productivity of oil wells.