Archean granite gneiss reservoirs are complex in lithology and rich in mineral types，with a large burial depth and high reservoir temperature，and high temperature has a significant impact on rock pore structure and flow characteristics.This paper used samples of Archean granite gneiss outcrops for experiments to evaluate the temperature sensitivity of permeability and the stress sensitivity under different temperatures and explore the response characteristics of permeability to temperature and effective stress. The results reveal that for the samples of granite gneiss blocks with permeability ranging from 0.1 mD to 1 mD，the permeability under the room temperature of 20 ℃ and the effective stress of 20 MPa is 1.66-2.04 times higher than that under the reservoir temperature of 170 ℃ and the effective stress of 20 MPa，and the permeability declines exponentially with the rise in temperature. Under nitrogen flooding conditions，the stress sensitivity of granite gneiss reservoirs at 20 ℃ is moderately strong，and the stress sensitivity at 100 ℃ and 170 ℃ is moderately weak，which tends to weaken with the increase in temperature. A moderate temperature within 200 ℃ is beneficial to improve rock strength and weakens the stress sensitivity of rock.